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8 Best Niacinamide Serums for Acne Treatment

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The answer to what you were looking for to control your acne-prone skin might be niacinamide. You’ve probably heard of it, as it’s commonly used in skincare products that address basically all skin concerns: acne, excess sebum, wrinkles, hyperpigmentation, or dry skin. And if you haven’t heard of it, here’s exactly what you need to know before purchasing a niacinamide serum to fight acne.

What is niacinamide?

In skincare, niacinamide is an antioxidant. Technically, it’s a form of vitamin B-3, water-soluble, that works with other natural substances in your skin to improve skin tone, minimize large pores, soften fine lines, and diminish acne. Yes, one element can do all these things!

How niacinamide attacks acne?

When applied topical daily, niacinamide may positively influence your skin health by reducing inflammation and acne-causing bacteria, smoothing the overall texture and brightening your skin. Niacinamide is also great in regulating the amount of sebum and prevent sebaceous glands from producing excessive oil.

Not only that niacinamide helps build cells in the skin, but it also protects from environmental stresses like toxins, sunlight, and pollution. Due to its ability to improve the skin’s barrier, niacinamide reduces the impact of free radical damage and helps skin repair itself, which is excellent for scars left by pimples.

A study published in the International Journal of Dermatology showed that 4% Niacinamide treated acne, with comparable results to a topical antibiotic. The experiment states that niacinamide helps treat acne due to its anti-inflammatory, antibacterial, and sebum-reducing properties.

Why in a serum

Because serums have smaller particles, they penetrate the skin on a deeper cellular level and faster, working more effectively. The beauty of serums is that they provide a higher concentration of active ingredients. The higher the concentration and deeper penetration, the better it is for the skin to benefit from niacinamide’s amazingly properties.

How it should be applied

First upfront, start by being patient, as you’re looking for at least two months of daily use of your niacinamide serum before you can expect noticeable results. This because niacinamide is gentle on the skin, unlike more aggressive skin treatments, and is less likely to irritate your skin.

Use your niacinamide serum every morning, and evening, after cleansing your complexion and after you’ve used the toner. Follow with moisturizer/SPF after you’ve applied the niacinamide serum.

8 Best Niacinamide Anti-Acne Serums

To make the job super easy for you, we’ve picked 8 serums infused with niacinamide, with as clean and natural formulas as possible. And so that your skin absorbs even more benefic nutrients, these serums are also enhanced with hyaluronic acid, antioxidants, vitamins, zinc, or retinol. Check them out!


Joyal Beauty Store Niacinamide Serum

Joyal Beauty Store Niacinamide Serum

Joyal Beauty’s serum B3 B5 facial serum contains a 5% concentration of niacinamide, which improves uneven skin tone, enlarged pores, fine lines, and hyperpigmented spots. The zinc in its formula, makes it beneficial for acne-prone skin, promising to diminish blemishes. Oil-free yet super hydrating, it restores moisture with hyaluronic acid while being a great makeup base.


Naturium Store Niacinamide Serum for Acne

Naturium Store Niacinamide Serum

The holly-grail of niacinamide serums, this one contains pure 12% niacinamide and 2% zinc that helps refine skin tone and minimizes the look of your pores, skin texture, and fine lines. Very concentrated, it helps purify and refine your complexion while retaining moisture thanks to the hyaluronic acid in it—no wonder why it got five stars out of 5.


Paula's Choice Niacinamide Concentrated Serum

Paula’s Choice CLINICAL 20% Niacinamide Concentrated Serum

The advanced 20% niacinamide concentration serum targets clogged pores, bumps, and discolorations, doing an excellent job! With vitamin C and licorice root extract, Paula’s Choice product makes a noticeable difference in your skin within just a few days of using it. Its safe and effective formula is cruelty-free, and Leaping Bunny certificated!


The Ordinary Niacinamide Treatment for Acne

The Ordinary Niacinamide Treatment for Acne

A dream came true for oily skin; this potent serum reduces acne-causing bacteria and minimizes pores by regulating sebum production. Featuring a high concentration of two of the most efficacious blemish-battling ingredients, niacinamide and zinc, this product soothes skin and improves its overall appearance. The shot of zinc also helps repair damaged skin and encourages the production of collagen synthesis.


Tree Of Life Niacinamide Face Moisturizer Serum

Tree Of Life Niacinamide Face Moisturizer Serum

One of the brands we like a lot, Tree Of Life, has such a clean formula that’s also enriched with hyaluronic acid and vitamin E. Skin spot reducer, collagen booster, and superior moisturizer that can also serve as a makeup base. 100% vegan and cruelty-free, you can enjoy high-quality skincare and feel secure knowing that you’re not applying harsh chemicals on your skin.


QRxLabs Niacinamide and Retinol Serum

QRxLabs Niacinamide and Retinol Serum

This Niacinamide serum may be the solution you have wished for. The reason? It combines niacinamide and retinol with organic aloe vera, vitamin E, jojoba oil, hyaluronic acid, and a cocktail of natural extracts, resulting in a rich consistency that’ll blow you away. QRxLabs Niacinamide Serum is the right product in your arsenal to slow down aging signs while diminishing breakouts.


I DEW CARE Purifying Face Serum with Niacinamide

I DEW CARE Purifying Face Serum with Niacinamide

K-beauty induces this supercharged serum like a green juice for blemish-prone skin thanks to a balancing blend of niacinamide, zinc, kale, spirulina chlorella, plus a purifying complex to help soothe and clear the complexion. Because this product contains a beta-hydroxy acid (BHA) that may increase your skin’s sensitivity to the sun, use sunscreen and limit sun exposure while using it and for a week afterward.


Cos De BAHA Niacinamide Anti-Acne Serum

Cos De BAHA Niacinamide Anti-Acne Serum

Cos De BAHA has a fantastic serum with 10% niacinamide and 1% zinc that addresses breakouts, blemishes, red marks, and irritated skin for an affordable price. With regular use, you’ll observe a pores’ appearance reduction and increased skin elasticity due to the addition of hyaluronic acid. In plus, this product contains 78% ingredients from organic sources — no reason not to try it out. With a surprisingly small price tag, this potent serum is perfect for combating blemishes, enlarged pores, and uneven skin tone.


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To our readers

The information from this article is not entirely medical-grade level and should not be treated as a substitute for medical advice from your doctor. No one will know you, your medical history, the meds you’ve taken or are taking, your sensitivities and drug interactions, allergic reactions, and your lifestyle, but your doctor does.

Amanda Blake
Amanda Blake
Amanda Blake is a passionate woman sharing experience as a beauty advisor and content writer for over 5 years. Merging all the passion with much work, she established Women's Concept community, a place where women can seek and share everything about beauty and personal care.

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