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9 Best Hyaluronic Acid Serums to Diminish Fine Lines & Wrinkles

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We all know what hyaluronic acid (HA) is — a super absorbent molecule that’s naturally found in our body and is mainly used to hydrate & soften the skin. You rarely find someone that doesn’t have a product with HA in their beauty routine, especially after turning 25. After all, everyone loves it. This substance is naturally produced by our bodies and can hold up to 1,000 times its weight in water, giving the skin plumper & softer texture. Crazy, I know. Because the skin’s hyaluronic acid level decreases with age, we need a serum to compensate for the loss. Otherwise, wrinkles and fine lines may appear more visible.

There are three types of hyaluronic acids (hydrolyzed hyaluronic acid, sodium acetylated hyaluronate, sodium hyaluronate), each having different molecular weights. The high molecular weight gives instant moisturizing film on the skin’s superficial layer and reduces transepidermal water loss.

HA with low molecular weight provides more hydration, aiming to improve fine lines, while the extra-low one can go even deeper into the skin layers improving skin texture, fine lines, being the most hydrating one. All three hyaluronic acid molecules inhabit hydrating properties and are humectants, that’s their superpower. They also have the ability to pull in moisture from the environment and absorb it onto your skin, locking the hydration into your skins’ top layers. OFC, you might find some products combining them all for maximum effectiveness.


Serums with Hyaluronic Acid

I know you need a HA serum that’ll smooth out the apparition of wrinkles. Here they are:

HA Serum

Peter Thomas Roth Water Drench Serum

Peter Thomas product is definitely one of the very best hydrating serums, locking in hydration for up to 72 hours, even after cleansing. With 75% hyaluronic acid, it helps keep your skin hydrated with an invisible veil of moisture, imparting a look of youthful radiance while also smooths out fine lines and rough texture. Bonus: it contains a derivative of pure silk in a water-soluble form, which leaves your skin soft, and a mineral complex of bio-fermented zinc, copper, magnesium, and iron to provide antioxidant benefits.

L’Occitane Immortelle Precious Serum

L’Occitane Immortelle Precious Serum 

L’occitane’s serum is made with Corsican Immortelle essential oil, a low-molecular-weight HA complex designed to power up the skin’s ability to renew itself. At the same time, lentil extract helps reduce the look of large pores. With maximum potency, this serum helps skin fight daily aggressors’ effects while correcting fine lines and maintaining skin firmness — and it absorbs in the blink of an eye.

Filorga HA serum

Filorga Hydra-Hyal Intensive Hyaluronic Acid Serum

This serum hydrates, smoothens, and plumps for a looong-lasting effect. Your skin gets immediately hydrated, and its radiance and suppleness are visibly restored. The sodium hyaluronate and sweet almond oil assure complete hydration all day long, while the folic acid provides increased moisture by bolstering skin-barrier function. It’s like a big drink of water for thirsty skin.

Sesderma Hidraderm Hyal Moisturizing Serum

Sesderma Hidraderm Hyal Moisturizing Serum

Boost hydration level, restore lost elasticity and keep your skin healthy all day long with all 3 hyaluronic acid molecule sizes. Not only hydrate the top layer of the skin, but it also goes deep inside the skin for wrinkle repair. Also, the blend of ceramide concentrate, fatty acids, and phytosphingosine strengthens the skin barrier to keep irritants out while hydrating it even more. Dehydrated, wrinkled skin will love it!

Harmonie Divine Serum

L’Occitane Harmonie Divine Serum

I know what you’re thinking, this serum is kinda pricey, but it’s one of the worth-every-penny serums out there. L’Occitane encapsulated Immortelle Millésimée (antioxidant and anti-aging activity) with Jania Rubens – the red algae known for its ability to eternally regenerate, organic onager oil, rich in omega 6, honey, and hyaluronic acid, to name just a few, in one product. Its purpose is to fight aging signs and reveal smoother-looking skin, and it does a damn-really good job at it! As well as being all-natural, this serum, eco-friendly and cruelty-free.

Hyaluronic Acid Anti-Aging Serum

ISDINCEUTICS Vitamin C and Hyaluronic Acid Serum Ampoule

Indeed, serums in ampoules are higher concentrated, so for your HA and vitamin C hit, try this! While you know how much moisture hyaluronic acid adds to your skin, you should know that vitamin C is its greatest ally, acting as an antioxidant, restore brightness and protect your skin from free radicals damage. Bonus: These ampoules contain magnesium that speeds up cellular regeneration too.

Skinception Instant Wrinkle Reducer

An organic anti-aging serum gives you an instant solution to fine lines and wrinkles. Like a primer, it smoothens out your skin for an impeccable finish. But, it also goes a step further and penetrates deeper into the layers of your skin to hydrate and renew your cells. Using a revolutionary formula, Skinception Instant Wrinkle Reducer features 3 main active ingredients: hyaluronic acid, hydrolyzed collagen, and Argireline. When you want to combat aging signs, this trio can do wonders — try it yourself!

Pure Hyaluronic Acid Serum

La Roche-Posay Hyalu B5 Pure Hyaluronic Acid Serum

Award winner of The Zoe Report Beauty Awards

This serum is formulated with pure hyaluronic acid, vitamin B5, Madecassoside, and La Roche-Posay Thermal Spring Water. Oil- and paraben-free, non-comedogenic, with an ophthalmologist and allergy-tested formula, it’s suitable even for sensitive skin. It has a texture that leaves skin feeling supple and hydrated to the touch all day long. You only need to apply 3-4 drops AM/PM to your face & neck for results that’ll amaze you!

StriVectin serum with HA

StriVectin Advanced Acid Hyaluronic Serum

This dual-chamber serum is basically a collection of high-performance formulas for aging skin that promotes hydration and moisture for a firmer look. Advanced serum combined the most potent, skin-transforming acids with patented NIA-114 technology (an optimized form of vitamin B3), proven to supercharge other ingredients’ performance for youthful-looking skin. Because it combines hyaluronic acid, vitamin C, and ceramides, it visibly plumps skin, preventing water loss — a real boost for thirsty skin.


  1. Hyaluronic Acid and Glycolic Acid Together: Can We Mix Them?
  2. Hyaluronic Acid and Retinol: How to Use Them Together
  3. 14 Best Lactic Acid Serums To Tackle Your Skin Concern
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