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6 Best Hyaluronic Acid Serums to Diminish Fine Lines & Wrinkles

Best Hyaluronic Acid Serums For Wrinkles
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Hyaluronic acid is mostly used to hydrate & soften the skin, being a super absorbent molecule that’s found naturally in our body.

Skin becomes less supple and firm as we age, so applying daily a hyaluronic acid serum can plump and smooth fine lines and wrinkles.

In cosmetics, there are two molecular sizes of hyaluronic acid that can be used in formulations: high-molecular and low-molecular-weight.

Hyaluronic acid with low-molecular-weight is split into smaller fragments, and can, therefore, reach the deeper layers of skin. There, it sustains the skin’s hydration and has a better regenerating effect once absorbed by the skin.

On the other hand, the high molecular weight HA remains closer to the surface, hydrating more, but the effect is shorter as it will be washed away once you cleanse your complexion.

Why Hyaluronic Acid is a Great Ally Against Aging

After reaching 35-40 years old, most women begin to seek ways to look younger and feel more confident. Hyaluronic acid is definitely one potent ally against aging signs.

Not many elements deliver what HA does. This substance is naturally produced by our bodies and is able to hold up to 1,000 times its weight in water, giving the skin plumper & softer texture. On top of that, it prevents the apparition of fine lines and wrinkles.

Our skin tissue naturally produces HA, maintaining its elasticity and firmness. But because the skin’s level of hyaluronic acid decreases with age, it’s highly recommended to maintain the hydration and moisture with a serum that contains hyaluronic acid.

Hyaluronic Acid Skin Benefits

Hyaluronic acid is known for its skin benefits, especially alleviating dry skin, minimizing the appearance of fine lines & wrinkles, and speeding up wound healing.

Also, it’s used for injecting into the knee, or for various joint disorders, acting as a cushion and lubricant in the joints and other tissues.

Besides injecting hyaluronic acid into the deeper layers in our skin, serums are a great and efficient complementary action to maintain a youth-looking appearance.

If you want to get the best of hyaluronic acid serums benefits, it’s ideal to always look for serums that do not contain harmful ingredients, such as parabens, dyes, sulfates, or alcohol.

6 Of The Best Anti-Aging Serums with Hyaluronic Acid

Considering you are ready to experience the hyaluronic acid benefits, read about the best hyaluronic acid serums based on real reviews.

ISDINCEUTICS Hyaluronic Acid Anti-Aging Serum

The potent antioxidants fight the visible signs of skin aging, providing in-depth, lasting moisture care, boosting hydration, while protecting skin against oxidative stress, and restoring elasticity. Also, the vitamin C restores brightness and protect skin from free radical damage.

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One of our favorite brands come with a solution in vials, aiming to improve fine lines, wrinkles, and leave your skin moisturized.

This anti-aging serum is ideal for a healthy glow and radiant complexion — soft, beautiful, and intensely moisturized skin after each application. It’s a supercharged antioxidant serum designed to protect against oxidative stress and deeply hydrate skin for a natural, radiant glow. Always shake the serum before you apply it all over the face, and neckline.

It’s formulated with a particular combination of proteoglycans and pre-proteoglycans, which supports firmness and elasticity in the skin and provide radiance. This substance has the capacity to bind to water in the skin and restore moisturizer levels.

Peter Thomas Roth Water Drench Serum

 Hyaluronic Acid Anti-Aging Serum

It helps replenish the appearance of dehydrated skin with vital moisture, imparting a look of youthful radiance while also smooths out the appearance of fine lines and rough texture.

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This serum assures intense hydration with a super-concentrated formula. With 75% hyaluronic acid, it helps to keep your skin hydrated with an invisible veil of moisture. 


Furthermore, its formula includes derivative of pure silk in a water-soluble form, leaving the skin soft, and a mineral complex of bio-fermented zinc, copper, magnesium & iron to provide antioxidant benefits.

This is definitely a potent hydrating serum that helps lock in hydration for up to 72 hours, even after cleansing.

Apply as needed to face and neck for intense hydration, and you will notice your skin’s appearance it’ll improve in less than one month of daily use.

Filorga Hydra-Hyal Intensive Hyaluronic Acid Serum

Anti-Aging Best Serum

Filorga’s Hyaluronic Acid serum hydrates, smoothens, and plumps for a long-lasting youth-enhancing effect. Your skin gets immediately hydrated from within, and its radiance and suppleness are restored.

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We decided to add this product because it’s adored by a lot of women and it has many positive reviews. Maybe it isn’t the most natural product in our list, but if you wish for faster results, this is what you’re looking for.

The sweet almond oil assures complete hydration all day long, while the folic acid provides increased moisture by bolstering skin-barrier function.

Apply it daily, morning & evening, before the moisturizer and you’ll shortly notice an improvement of plumped fine lines and wrinkles.

La Roche-Posay Hyalu B5 Pure Hyaluronic Acid Serum

La Roche-Posay Hyalu Pure Hyaluronic Acid Serum

An award winner of The Zoe Report Beauty Awards, Affordable Beauty 2018, this serum is appreciated by a lot of women, being still one of the most popular products.

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This fantastic anti-aging serum is formulated with pure hyaluronic acid, vitamin B5, Madecassoside, and La Roche-Posay Thermal Spring Water. 

You only need to apply 3-4 drops every morning and evening to the face & neck, and the results will amaze you!

It is oil- and paraben-free, non-comedogenic, with an ophthalmologist, and allergy-tested formula, and is suitable for sensitive skin.

Rich serum by La Roche Posay has a texture that leaves skin feeling supple and hydrated to the touch. Fine lines are reduced, and skin feels plumped as if renewed.

StriVectin Advanced Acid Hyaluronic Serum

Serum with Hyaluronic Acid

This dual-chamber serum is basically a collection of high-performance formulas for aging skin that promotes hydration and moisture for a firmer complexion.

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You can get rid away of fine lines & wrinkles with StriVectin Dual-response serum that hydrates intensely, strengthening the skin barrier for lasting moisture.

Advanced Acids serum combined the most potent, skin-transforming acids with patented NIA-114 technology, which is an optimized form of vitamin B3, clinically proven to supercharge the performance of other ingredients for more youthful-looking skin. 

In order to get its best benefits is recommended to be applied in the morning & in the evening before moisturizer, avoiding the eye area. Because it contains six forms of hyaluronic acid, it visibly plumps skin, preventing water loss. It’s a really great product for when your skin needs an additional boost.

Radha Beauty Hyaluronic Acid Serum

 HA Serum

Achieve a youthful radiance, boost hydration level, restore lost elasticity, and keep your skin healthy all day long with this natural serum, ideal for fine lines and wrinkles.

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You should try Radha Hyaluronic Acid Serum if you want an organic approach. 

Besides hyaluronic acid, its formula also includes vitamins C and E, green tea and jojoba oil to help you prevent the apparition of fine lines. 

This collagen booster is ideal for face, neck, and décolletage, and also for eye area because it does not contain fillers, fragrances, alcohol, sulfates, PABs, dyes, or parabens. Keep your skin supple and hydrated, and prevent the apparition of early wrinkles with Radha Hyaluronic Acid serum that has a thin consistency for better absorption.

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  • published on July 2012 by Eleni Papakonstantinou
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To our readers

The information from this article is not entirely medical-grade level and should not be treated as a substitute for medical advice from your doctor. No one will know you, your medical history, the meds you’ve taken or are taking, your sensitivities and drug interactions, allergic reactions, and your lifestyle, but your doctor does.

Virginia Decker
Virginia Decker
Virginia Decker is one of the most experienced members of our team. With over 20 years of practice in the skincare field, she always shares the best and most transparent information to our community.
1 Comment
  • So far, so good!! happy Sunday!

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